Natural Product Library

NATURAL PRODUCT LIBRARY OVERVIEW

PhytoPharmacon has a collection of over 10,000 plant and microbial extracts from over 5,000 plants and microbial species. These unique collections are readily available for a very reasonable price on a non-exclusive basis and are subdivided into four diverse sets:

PURE COMPOUND LIBRARIES:

PhytoPharmacon has about 1000 pure compounds isolated from plants and microbes based on assay-guided fractionations. About 25% of the compounds have structural information.

HIGHLY ENRICHED PHYTOCHEMICALS:

The 20,000 highly enriched phytochemicals have been generated from plant extracts by polyamide gel chromatography and solid phase extractions. Each fraction contains 1-4 compounds, highly enriched. These fractions contain low molecular weight compounds (ranging from 200-600 molecular weight).

PhytoPharmacon has a large collection of USA based medicinal plants. Plants used for extraction in plant libraries were grown by exploratory seed collection and cultivation in NC farms. We also have an unexplored and unique collection of endophytic microbes and pure natural product compounds. We are ready to address the sourcing issues for the clients and offer custom screening, crop scale up, down-stream processing and supercritical fluid extraction PhytoPharmacon has many satisfied customers including pharmaceutical, nutraceutical, cosmetic and agri-biotech companies.

PLANT LIBRARIES:

Plant extracts are available in bulk (>5 g quantity), in vials (10 mg), in 96-well plates (1 mg/well) as well as highly-enriched phytochemical fractions.

  • PhytoPharmacon offers a unique collection of plants with an extensive ethnobotanical database.
  • Plants are harvested fresh, extracted and purified by passing through polyamide gel to remove assay interfering materials.
  • We have experience in cultivating these plants in both green house and field conditions
  • Most of the plants are from the Southeastern United States and Mexico, and a unique collections from India.
  • The genetic materials are available to grow the plants on a large scale to circumvent any potential supply issues.

MICROBIAL LIBRARIES:

The microbial library consists of extracts of endophytes (fungi), actinomycetes, bacteria and yeasts. We have over 5,000 extracts obtained from fungal endophytes isolated from medicinal plants. We have used the following previously unexplored microbial sources for the production of novel microbial metabolites:

  • Endophytes from medicinally important plants (~2000 cultures).
  • Actinomycetes from unique environments such as estuaries, and sledges (~1600 cultures).
  • Extracts from approximately 500 yeast and bacteria.

FLAVORING LIBRARIES:

PhytoPharmacon has a large collection of PLANT EXTRACTS and PLANT PROTEINS as potential leads for novel flavoring agents, flavor enhancement and taste modulation for food and beverage industries. Plants used for extraction are grown by exploratory seed collection and cultivation in the NC farms. We offer large scale cultivation in greenhouses and fields, down-stream processing and supercritical fluid extraction in two distinct geographical locations in North Carolina, USA and Southern India.

PhytoPharmacon offers about 1000 Plant Extracts as potential leads for novel flavoring agents, flavor enhancement and taste modulation for food and beverage industries. The plants were preselected based on the following criteria:

  • Plants are highly enriched in aromatic and organoleptic compounds.
  • Ability to scale-up to large quantities.
  • Availability of germplasm for the growth in multiple acres in the USA.
  • A long history of traditional use for smell and taste.